Projects

Sleepy Eyes drowsy driving detection

By: Thomas X.Year: 2021School: Yorba Linda HighGrade: 11Science Teacher: Daniel Eliot Drowsy driving can be lethal. Although, determining a precise number of drowsy-driving crashes, injuries, and fatalities is not yet possible, the National Highway Traffic Safety Administration (NHTSA) estimates that in 2017, 91,000 police-reported crashes involved drowsy drivers. These crashes led to an estimated 50,000 people

Assessing Grass Water Use Efficiency Through Smartphone Imaging and ImageJ Analysis

By: Aniyah S.Year: 2021School: University HighGrade: 10Science Teacher: Shannon Bunch Overwatering and underwatering are widespread issues with extensive consequences. Current approaches to assess water use efficiency (WUE) are inaccessible or indirect. Hypothesis: Smartphone imaging combined with ImageJ analysis is an effective method to determine ideal watering ranges and assess grass WUE. Aniyah examined how nine

Plant Stress Response to Climate Change Induced Salinity: Identifying Biomarkers by Liquid Chromatography Mass Spectrometry

By: Matthew C.Year: 2021School: South Lake MiddleGrade: 8Science Teacher: Jamie Sodorff Climate change is one of the most pressing issues of the century. As temperatures increase and our oceans acidify, we must be vigilant in shifting our world to renewable energy sources or be prepared to address global issues such as food insecurity and agricultural

Immunotherapy Tumor Suppression (ITS): Using convolutional neural networks, gene profiling, and CRISPR/Cas9 Base Editing to enhance genetically engineered Chimeric Antigen Receptor T-cells for efficient immunotherapy

By: Pranav S. & Vishnu M.Year: 2021School: Irvine HighGrade: 11Science Teacher: Neetu Toura The purpose of this software was to design a tumor suppression immunotherapy from tumors identified by medical scans (CT and MRI). This was done utilizing CAR-T cells, a type of lymphocyte that targets and kills rapidly dividing tumor cells. Normal T-cells target

The antimicrobial effect of common spices on the growth of fungi

By: Harleen A.Year: 2021School: Irvine HighGrade: 10Science Teacher: Crystal Cooper Fungi (yeasts and molds) cause food spoilage and contribute to food-borne disease incidence. Mycotoxins produced by these types of molds are often associated with several diseases. Since ancient times, many spices have been used for food preservation, and this study examines some of those common

Investigating Effective Alternatives to Silver-based Pressure Sore Treatments and Other Novel Applications of Gold and Copper Nanoparticles

By: Arjun G.Year: 2021School: Los Alamitos HighGrade: 9Science Teacher: Shereen Awad Recently after undergoing a major surgery, Arjun’s grandfather developed a pressure sore on his tailbone that dug deep into his skin to the point that the bone was visible. To help treat the pressure sore, he was prescribed a silver nanoparticle-based medication. Because silver

Dietary Flavonoid Dihydromyricetin (DHM) Ameliorates Alcohol-Induced Intestinal Microbiome Changes Associated with Alcoholic Liver Disease

By: Le Ann T.Year: 2021School: Arnold O. Beckman HighGrade: 10Science Teacher: Siu Kong Sit Chronic alcohol consumption contributes to systemic, multi-organ injury. In addition to multi-organ injury, chronic alcohol abuse has been found to shift microbiome populations in the small intestines. Dihydromyricetin (DHM), a natural flavonoid, significantly reduces alcoholic liver disease (ALD) outcomes following chronic

New Brain Computer Interfaces for Neurologically Impaired Subjects Augmented with Gaming Technology to Improve Cognitive functions in ADHD Subjects

By: Nithin P.Year: 2021School: Northwood HighGrade: 11Science Teacher: Jane Yoon Amyotrophic lateral sclerosis (ALS), a progressive neuromuscular degenerative disease, restricts patients’ communication capacity a few years after onset resulting in a severe degradation in their quality of life. ALS patients currently have a means to communicate through non-invasive brain-computer interfaces (BCI). This research adapts and