Hepatitis B Patient-Derived Virus Shows Replication Step-Dependent Resistance to Interferon Treatment in an In-Vitro Chronic Infection Model

By: Annabel T.Year: 2023School: Northwood HighGrade: 12Science Teacher: Karen Zhou Hepatitis B virus (HBV) infection is a major global health concern, affecting approximately 300 million people worldwide. Despite significant advancements in medical science, there is still no definitive cure for chronic HBV infection. Interferon (IFN), an antiviral cytokine, represents the first-line treatment for HBV patients. However, clinical studies …